Occlusion and stenosis of arteries, not leading to stroke

I9_STENOSIS

intracranial embolism: Blocking of a blood vessel in the skull by an embolus which can be a blood clot (thrombus) or other undissolved material in the blood stream. Most emboli are of cardiac origin and are associated with heart diseases. Other non-cardiac sources of emboli are usually associated with vascular diseases.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I66

Hospital discharge: ICD-9 4330X|4331X|4339X

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 I66

Cause of death: ICD-9 4330X|4331X|4339X

Cause of death: ICD-8 $!$

318

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

318

Check minimum number of events None

318

Include endpoints None

318

I9_STENOSIS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 I60-I69

Name in latin Occlusio sive stenosis arteriarum cerebralium sine infarctu

Similar endpoints

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List of similar endpoints to Occlusion and stenosis of arteries, not leading to stroke based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

306

101

205

Unadjusted prevalence (%)

0.10

0.06

0.15

Mean age at first event (years)

61.79

61.72

61.83

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_STENOSIS – Occlusion and stenosis of arteries, not leading to stroke
GWS hits: 1

Survival analyses between endpoints

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Plot

before Occlusion and stenosis of arteries, not leading to stroke
after Occlusion and stenosis of arteries, not leading to stroke

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Table

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Drugs most likely to be purchased after Occlusion and stenosis of arteries, not leading to stroke

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