Occlusion and stenosis of arteries, not leading to stroke

I9_STENOSIS

intracranial embolism: Blocking of a blood vessel in the skull by an embolus which can be a blood clot (thrombus) or other undissolved material in the blood stream. Most emboli are of cardiac origin and are associated with heart diseases. Other non-cardiac sources of emboli are usually associated with vascular diseases.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 I66
Hospital discharge: ICD-9 4330X|4331X|4339X
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I66
Cause of death: ICD-9 4330X|4331X|4339X
Cause of death: ICD-8 $!$

318

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

318

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Check minimum number of events None

318

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Include endpoints None

318

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I9_STENOSIS

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I60-I69
Name in latin Occlusio sive stenosis arteriarum cerebralium sine infarctu

Summary Statistics

Key figures

All Female Male
Number of individuals 306 101 205
Unadjusted prevalence (%) 0.10 0.06 0.15
Mean age at first event (years) 61.79 61.72 61.83

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_STENOSIS – Occlusion and stenosis of arteries, not leading to stroke
GWS hits: 1

Survival analyses between endpoints

Plot

before Occlusion and stenosis of arteries, not leading to stroke
after Occlusion and stenosis of arteries, not leading to stroke

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Drugs most likely to be purchased after Occlusion and stenosis of arteries, not leading to stroke