Unspecified diabetes

E4_DMNAS

diabetes mellitus: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E12

Cause of death: ICD-10 E12

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

Check minimum number of events None

Include endpoints

E4_DMNASCOMA

E4_DMNASKETO

E4_DMNASREN

E4_DMNASOPTH

E4_DMNASNEU

E4_DMNASPERIPH

E4_DMNASNASCOMP

E4_DMNASOTHCOMP

E4_DMNASNOCOMP

E4_DMICD8

6105

E4_DMNAS

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF3

Parent code in ICD-10 E10-E14

Name in latin Diabetes mellitus malnutritionalis

Similar endpoints

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List of similar endpoints to Unspecified diabetes based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	5920	2966	2954
Unadjusted prevalence (%)	1.92	1.71	2.19
Mean age at first event (years)	39.85	36.52	43.19

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.96 [3.20, 4.90]	1.1e-36	1228
15 years	0.01	2.32 [1.96, 2.75]	2.8e-22	523
5 years	0.00	3.62 [3.07, 4.27]	7.6e-53	265
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DMNAS – Unspecified diabetes
GWS hits: 13

Survival analyses between endpoints

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Plot

before Unspecified diabetes
after Unspecified diabetes

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Unspecified diabetes

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