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Unspecified diabetes with neurological complications

DOIDEFOMESHSNOMED PheWeb

E4_DMNASNEU

diabetic neuropathy: A chronic, pathological complication associated with diabetes mellitus, where nerve damages are incurred due to diabetic microvascular injury involving small blood vessels that supply these nerves, resulting in peripheral and/or autonomic nerve dysfunction.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E12.4+, E13.4+, E14.4+
Hospital discharge: ICD-9 2505C|2505X
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E12.4+, E13.4+, E14.4+
Cause of death: ICD-9 2505C|2505X
Cause of death: ICD-8 $!$

91

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

91

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Check minimum number of events None

91

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Include endpoints None

91

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E4_DMNASNEU

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF3

Summary Statistics

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Key figures

All Female Male
Number of individuals 90 28 62
Unadjusted prevalence (%) 0.03 0.02 0.05
Mean age at first event (years) 53.98 51.95 54.90

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DMNASNEU – Unspecified diabetes with neurological complications
GWS hits: 0

Survival analyses between endpoints

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Plot

before Unspecified diabetes with neurological complications
after Unspecified diabetes with neurological complications

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Unspecified diabetes with neurological complications

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