Unspecified diabetes with ketoacidosis

E4_DMNASKETO

diabetic ketoacidosis: The metabolic condition resulted from uncontrolled diabetes mellitus, in which the shift of acid-base status of the body toward the acid side because of loss of base or retention of acids other than carbonic acid is accompanied by the accumulation of ketone bodies in body tissues and fluids.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E12.1, E13.1, E14.1

Hospital discharge: ICD-9 2501C|2501X

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E12.1, E13.1, E14.1

Cause of death: ICD-9 2501C|2501X

Cause of death: ICD-8 $!$

195

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

195

Check minimum number of events None

195

Include endpoints None

195

E4_DMNASKETO

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Unspecified diabetes with ketoacidosis based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	187	73	114
Unadjusted prevalence (%)	0.06	0.04	0.08
Mean age at first event (years)	49.52	50.29	49.03

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DMNASKETO – Unspecified diabetes with ketoacidosis
GWS hits: 1

Survival analyses between endpoints

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Plot

before Unspecified diabetes with ketoacidosis
after Unspecified diabetes with ketoacidosis

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Table

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Drugs most likely to be purchased after Unspecified diabetes with ketoacidosis

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