Unspecified diabetes without complications

E4_DMNASNOCOMP

diabetes mellitus: A metabolic disorder characterized by abnormally high blood sugar levels due to diminished production of insulin or insulin resistance/desensitization.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E12.9, E13.9, E14.9

Hospital discharge: ICD-9 2500C|2500X

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E12.9, E13.9, E14.9

Cause of death: ICD-9 2500C|2500X

Cause of death: ICD-8 $!$

2171

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

2171

Check minimum number of events None

2171

Include endpoints None

2171

E4_DMNASNOCOMP

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Unspecified diabetes without complications based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2088	887	1201
Unadjusted prevalence (%)	0.68	0.51	0.89
Mean age at first event (years)	53.58	52.37	54.48

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	5.77 [4.31, 7.72]	4.1e-32	411
15 years	0.01	2.18 [1.57, 3.02]	2.7e-6	140
5 years	0.00	4.58 [3.33, 6.29]	7.5e-21	124
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DMNASNOCOMP – Unspecified diabetes without complications
GWS hits: 1

Survival analyses between endpoints

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Plot

before Unspecified diabetes without complications
after Unspecified diabetes without complications

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Unspecified diabetes without complications

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