Type 1 diabetes


type I diabetes mellitus: A chronic condition characterized by minimal or absent production of insulin by the pancreas.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 E10
Cause of death: ICD-10 E10


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10


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Check minimum number of events None


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 E10-E14
Name in latin Diabetes (mellitus) juvenilis

Similar endpoints

List of similar endpoints to Type 1 diabetes based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 8671 4049 4622
Unadjusted prevalence (%) 2.81 2.33 3.42
Mean age at first event (years) 33.30 30.89 35.41


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 5.40 [4.35, 6.71] 1.7e-52 1135
15 years 0.02 3.20 [2.67, 3.83] 2.9e-36 513
5 years 0.00 4.91 [4.09, 5.88] 2.3e-66 275
1 year 0.00 9.30 [7.34, 11.78] 5.8e-76 112

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: E4_DM1 – Type 1 diabetes
GWS hits: 30

Survival analyses between endpoints


before Type 1 diabetes
after Type 1 diabetes

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