Type 1 diabetes with peripheral circulatory complications

DOID EFO MESH SNOMED PheWeb

E4_DM1PERIPH

diabetic angiopathy: VASCULAR DISEASES that are associated with DIABETES MELLITUS.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E10.5

Hospital discharge: ICD-9 2506B

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E10.5

Cause of death: ICD-9 2506B

Cause of death: ICD-8 $!$

555

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

555

Check minimum number of events None

555

Include endpoints None

555

E4_DM1PERIPH

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF3

Parent code in ICD-10 E10

Similar endpoints

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List of similar endpoints to Type 1 diabetes with peripheral circulatory complications based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	546	213	333
Unadjusted prevalence (%)	0.18	0.12	0.25
Mean age at first event (years)	49.67	46.68	51.58

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DM1PERIPH – Type 1 diabetes with peripheral circulatory complications
GWS hits: 4

Survival analyses between endpoints

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Plot

before Type 1 diabetes with peripheral circulatory complications
after Type 1 diabetes with peripheral circulatory complications

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Table

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Drugs most likely to be purchased after Type 1 diabetes with peripheral circulatory complications

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