Sub-endpoint used in defining T1D endpoints

T1D_ICD9_10

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 E10
Hospital discharge: ICD-9 250
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 E10
Cause of death: ICD-9 250
Cause of death: ICD-8 $!$

11343

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

10404

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Check minimum number of events None

10404

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Include endpoints None

10404

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T1D_ICD9_10

Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 E10-E14
Name in latin Diabetes (mellitus) juvenilis

Similar endpoints

List of similar endpoints to Sub-endpoint used in defining T1D endpoints based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

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Summary Statistics

Key figures

All Female Male
Number of individuals 10125 4606 5519
Unadjusted prevalence (%) 3.28 2.65 4.09
Mean age at first event (years) 36.76 34.31 38.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.05 3.72 [3.11, 4.44] 6.8e-48 1986
15 years 0.01 2.33 [2.03, 2.67] 1.9e-34 935
5 years 0.00 3.32 [2.93, 3.77] 1.6e-77 459
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: T1D_ICD9_10 – Sub-endpoint used in defining T1D endpoints
GWS hits:

Survival analyses between endpoints

Plot

before Sub-endpoint used in defining T1D endpoints
after Sub-endpoint used in defining T1D endpoints

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Drugs most likely to be purchased after Sub-endpoint used in defining T1D endpoints