Sub-endpoint used in defining T1D endpoints

PheWeb

T1D_ICD9_10

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E10

Hospital discharge: ICD-9 250

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E10

Cause of death: ICD-9 250

Cause of death: ICD-8 $!$

11343

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

10404

Check minimum number of events None

10404

Include endpoints None

10404

T1D_ICD9_10

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 E10-E14

Name in latin Diabetes (mellitus) juvenilis

Similar endpoints

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List of similar endpoints to Sub-endpoint used in defining T1D endpoints based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	10125	4606	5519
Unadjusted prevalence (%)	3.28	2.65	4.09
Mean age at first event (years)	36.76	34.31	38.80

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.72 [3.11, 4.44]	6.8e-48	1986
15 years	0.01	2.33 [2.03, 2.67]	1.9e-34	935
5 years	0.00	3.32 [2.93, 3.77]	1.6e-77	459
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: T1D_ICD9_10 – Sub-endpoint used in defining T1D endpoints
GWS hits:

Survival analyses between endpoints

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Plot

before Sub-endpoint used in defining T1D endpoints
after Sub-endpoint used in defining T1D endpoints

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Table

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Drugs most likely to be purchased after Sub-endpoint used in defining T1D endpoints

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