Type 1 diabetes with coma

DOID MESH PheWeb

E4_DM1COMA

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 E10.00, E10.01, E10.09

Hospital discharge: ICD-9 2502B

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 E10.00, E10.01, E10.09

Cause of death: ICD-9 2502B

Cause of death: ICD-8 $!$

1765

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1765

Check minimum number of events None

1765

Include endpoints None

1765

E4_DM1COMA

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF4

Similar endpoints

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List of similar endpoints to Type 1 diabetes with coma based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1732	819	913
Unadjusted prevalence (%)	0.56	0.47	0.68
Mean age at first event (years)	33.47	31.80	34.96

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.10	8.05 [4.89, 13.26]	2.4e-16	214
15 years	0.03	4.08 [2.43, 6.84]	1.0e-7	90
5 years	0.01	8.92 [5.88, 13.54]	7.0e-25	56
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: E4_DM1COMA – Type 1 diabetes with coma
GWS hits: 10

Survival analyses between endpoints

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Plot

before Type 1 diabetes with coma
after Type 1 diabetes with coma

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Table

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Drugs most likely to be purchased after Type 1 diabetes with coma

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