Vocal cord dysfunction


human african trypanosomiasis: A parasitic disorder caused by protozoa of the Trypanosoma brucei species. It is transmitted by flies and is endemic in various regions of Sub-Saharan Africa. Signs and symptoms include fever, joint pain, headache, and significant swelling of the lymph nodes. If left untreated, the parasitic infection causes anemia, heart, kidney, and endocrine failure, and neurologic damage. Subsequently patients develop confusion, disruption of the sleep cycle, and mental deterioration. The infection may lead to coma and death.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 J38.3
Hospital discharge: ICD-9 $!$
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 J38.3
Cause of death: ICD-9 $!$
Cause of death: ICD-8 $!$


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 J38
Name in latin Alii morbi plicarum vocalium

Summary Statistics

Key figures

All Female Male
Number of individuals 795 380 415
Unadjusted prevalence (%) 0.26 0.22 0.31
Mean age at first event (years) 55.41 52.61 57.97


Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.01 1.16 [0.35, 3.84] 8.0e-1 59
15 years 0.01 0.88 [0.32, 2.42] 8.0e-1 26
5 years 0.00 2.94 [1.34, 6.43] 6.9e-3 22
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: VOCALCORDDYS – Vocal cord dysfunction
GWS hits: 0

Survival analyses between endpoints


before Vocal cord dysfunction
after Vocal cord dysfunction

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Vocal cord dysfunction