Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

J10_VOCALLARYNX

laryngeal disease: A non-neoplastic or neoplastic disorder that affects the larynx. Representative examples include laryngitis, vocal cord polyp, squamous papilloma, and carcinoma. [database_cross_reference: NCIT:P378]

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 J34, J38, J39

Hospital discharge: ICD-9 478

Hospital discharge: ICD-8 508

Hospital discharge: excluded ICD-8 50803

Cause of death: ICD-10 J34, J38, J39

Cause of death: ICD-9 478

Cause of death: ICD-8 508

Cause of death: excluded ICD-8 50803

15609

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

15591

Check minimum number of events None

15591

Include endpoints None

15591

J10_VOCALLARYNX

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	15043	7543	7500
Unadjusted prevalence (%)	4.88	4.35	5.55
Mean age at first event (years)	47.93	46.56	49.31

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.54 [1.24, 1.92]	1.0e-4	887
15 years	0.01	0.98 [0.79, 1.20]	8.2e-1	387
5 years	0.00	2.15 [1.77, 2.62]	2.3e-14	218
1 year	0.00	5.96 [4.67, 7.60]	5.4e-47	115

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_VOCALLARYNX – Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified
GWS hits: 1

Survival analyses between endpoints

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Plot

before Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified
after Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

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Table

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Drugs most likely to be purchased after Diseases of vocal cords and larynx+other diseases of upper respiratory tract, no elsewhere classified

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