Diseases of the respiratory system

X_RESPIRATORY

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 J00-J06, J09-J18, J20-J22, J30-J39, J40-J47, J60-J70, J80-J84, J85-J86, J90-J94, J95-J99
Hospital discharge: ICD-9 4[6-9]|5[0-1]
Hospital discharge: ICD-8 4[6-9]|5[0-1]
Cause of death: ICD-9 4[6-9]|5[0-1]
Cause of death: ICD-8 4[6-9]|5[0-1]

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

161352

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X_RESPIRATORY

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 156039 80849 75190
Unadjusted prevalence (%) 50.57 46.59 55.69
Mean age at first event (years) 38.41 36.41 40.57

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 4.04 [3.78, 4.33] <1e-100 17808
15 years 0.01 2.25 [2.09, 2.43] 1.1e-99 6132
5 years 0.00 4.71 [4.37, 5.07] <1e-100 4440
1 year 0.00 22.83 [20.21, 25.79] <1e-100 4759

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: X_RESPIRATORY – Diseases of the respiratory system
GWS hits:

Survival analyses between endpoints

Plot

before Diseases of the respiratory system
after Diseases of the respiratory system

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Drugs most likely to be purchased after Diseases of the respiratory system