Acute upper respiratory infections

DOID EFO MESH SNOMED PheWeb

J10_UPPERINFEC

sinusitis: An acute or chronic inflammatory process affecting the mucous membranes of any sinus cavity.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 J00-J06

Cause of death: ICD-10 J00-J06

36888

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

36888

Check minimum number of events None

36888

Include endpoints

J10_COLD

J10_SINUSITIS

J10_PHARYNGITIS

J10_TONSILLITIS

J10_LARYNGITIS

J10_EPIGLOTTITIS

J10_ACUTEUPPERINFEC

55434

J10_UPPERINFEC

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Acute upper respiratory infections based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	53544	25778	27766
Unadjusted prevalence (%)	17.35	14.86	20.56
Mean age at first event (years)	32.45	36.05	29.11

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.61 [2.31, 2.96]	1.7e-52	2934
15 years	0.01	1.38 [1.22, 1.56]	2.8e-7	1102
5 years	0.00	2.89 [2.56, 3.25]	2.1e-67	828
1 year	0.00	7.69 [6.61, 8.93]	<1e-100	469

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_UPPERINFEC – Acute upper respiratory infections
GWS hits: 3

Survival analyses between endpoints

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Plot

before Acute upper respiratory infections
after Acute upper respiratory infections

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Table

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Drugs most likely to be purchased after Acute upper respiratory infections

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