Diseases of the respiratory system

PheWeb

J10_RESPIRATORY

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 J00-J06, J09-J18, J20-J22, J30-J39, J40-J47, J60-J70, J80-J84, J85-J86, J90-J94, J95-J99

Cause of death: ICD-10 J00-J06, J09-J18, J20-J22, J30-J39, J40-J47, J60-J70, J80-J84, J85-J86, J90-J94, J95-J99

126575

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

126575

Check minimum number of events None

126575

Include endpoints

J10_UPPERINFEC

J10_INFLUPNEU

J10_LOWERINF

J10_UPPERDIS

J10_LOWCHRON

J10_EXTERLUNG

J10_INTERSTITIUM

J10_NECROTIC

J10_PLEURA

J10_RESPOTHER

164802

J10_RESPIRATORY

Extra metadata

Level in the ICD hierarchy 1

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diseases of the respiratory system based on the number of shared cases.

Broader endpoints:

None

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	159375	83176	76199
Unadjusted prevalence (%)	51.65	47.93	56.43
Mean age at first event (years)	38.37	36.38	40.54

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	4.02 [3.75, 4.31]	<1e-100	17873
15 years	0.01	2.24 [2.07, 2.42]	3.0e-91	6192
5 years	0.00	4.54 [4.21, 4.90]	<1e-100	4377
1 year	0.00	22.03 [19.49, 24.90]	<1e-100	4677

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_RESPIRATORY – Diseases of the respiratory system
GWS hits: 15

Survival analyses between endpoints

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Plot

before Diseases of the respiratory system
after Diseases of the respiratory system

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Table

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Drugs most likely to be purchased after Diseases of the respiratory system

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