Suppurative and necrotic conditions of lower respiratory tract

J10_NECROTIC

pleural empyema: The presence of pus in the thoracic cavity, between the visceral and parietal pleura. [database_cross_reference: NCIT:P378]

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 J85-J86
Cause of death: ICD-10 J85-J86

1008

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

1008

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Check minimum number of events None

1008

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J10_NECROTIC

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 1074 280 794
Unadjusted prevalence (%) 0.35 0.16 0.59
Mean age at first event (years) 58.89 54.37 60.48

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.10 8.33 [5.75, 12.07] 3.5e-29 301
15 years 0.01 2.42 [1.61, 3.63] 2.0e-5 76
5 years 0.01 5.74 [3.68, 8.95] 1.4e-14 81
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: J10_NECROTIC – Suppurative and necrotic conditions of lower respiratory tract
GWS hits: 0

Survival analyses between endpoints

Plot

before Suppurative and necrotic conditions of lower respiratory tract
after Suppurative and necrotic conditions of lower respiratory tract

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Drugs most likely to be purchased after Suppurative and necrotic conditions of lower respiratory tract