Other diseases of the respiratory system

J10_RESPOTHER

respiratory system disease: A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 J95, J96, J98

Cause of death: ICD-10 J95, J96, J98

4008

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

4008

Check minimum number of events None

4008

Include endpoints

J10_RESPDISOTH

4737

J10_RESPOTHER

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other diseases of the respiratory system based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

4605

1741

2864

Unadjusted prevalence (%)

1.49

1.00

2.12

Mean age at first event (years)

61.76

58.77

63.58

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Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	6.35 [4.71, 8.55]	5.5e-34	1668
15 years	0.01	1.85 [1.43, 2.39]	2.9e-6	366
5 years	0.00	0.26 [0.03, 2.12]	2.1e-1	536
1 year	0.01	34.50 [29.50, 40.36]	<1e-100	692

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_RESPOTHER – Other diseases of the respiratory system
GWS hits: 0

Survival analyses between endpoints

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Plot

before Other diseases of the respiratory system
after Other diseases of the respiratory system

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Table

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Drugs most likely to be purchased after Other diseases of the respiratory system

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