Other diseases of the respiratory system

J10_RESPOTHER

respiratory system disease: A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 J95, J96, J98
Cause of death: ICD-10 J95, J96, J98

4008

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

4008

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Check minimum number of events None

4008

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Include endpoints

4737

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J10_RESPOTHER

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 4605 1741 2864
Unadjusted prevalence (%) 1.49 1.00 2.12
Mean age at first event (years) 61.76 58.77 63.58

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 6.35 [4.71, 8.55] 5.5e-34 1668
15 years 0.01 1.85 [1.43, 2.39] 2.9e-6 366
5 years 0.00 0.26 [0.03, 2.12] 2.1e-1 536
1 year 0.01 34.50 [29.50, 40.36] <1e-100 692

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: J10_RESPOTHER – Other diseases of the respiratory system
GWS hits: 0

Survival analyses between endpoints

Plot

before Other diseases of the respiratory system
after Other diseases of the respiratory system

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Drugs most likely to be purchased after Other diseases of the respiratory system