Other diseases of pleura

J10_PLEURA

respiratory system disease: A non-neoplastic or neoplastic disorder that affects the respiratory system. Representative examples include pneumonia, chronic obstructive pulmonary disease, pulmonary failure, lung adenoma, lung carcinoma, and tracheal carcinoma.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 J90-J94, J95-J99

Cause of death: ICD-10 J90-J94, J95-J99

10780

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

10780

Check minimum number of events None

10780

Include endpoints

J10_PLEUREFFUSION

J10_PLEURPLAGUE

J10_PNEUMOTHORAX

J10_PLEUROTH

11600

J10_PLEURA

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Other diseases of pleura based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	11267	3660	7607
Unadjusted prevalence (%)	3.65	2.11	5.63
Mean age at first event (years)	63.18	60.78	64.34

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	5.36 [4.50, 6.38]	1.7e-78	3451
15 years	0.01	1.81 [1.54, 2.12]	2.2e-13	849
5 years	0.01	5.52 [4.88, 6.25]	<1e-100	1047
1 year	0.01	30.38 [26.81, 34.43]	<1e-100	1403

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: J10_PLEURA – Other diseases of pleura
GWS hits: 1

Survival analyses between endpoints

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Plot

before Other diseases of pleura
after Other diseases of pleura

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Table

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Drugs most likely to be purchased after Other diseases of pleura

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