Cardiomyopathy

I9_CARDMYO

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I42

Cause of death: ICD-10 I42

4468

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

4468

Check minimum number of events None

4468

Include endpoints

I9_CARDMPRI

I9_CARDMSEC

I9_CARDMYOHYP

I9_CARDMYOALC

I9_CARDMYORESTR

I9_CARDMYOOTH

I9_CARDMYOINOTH

4723

I9_CARDMYO

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 I30-I52

Name in latin Cardiomyopathia

Similar endpoints

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List of similar endpoints to Cardiomyopathy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	4606	1511	3095
Unadjusted prevalence (%)	1.49	0.87	2.29
Mean age at first event (years)	59.12	57.73	59.80

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	6.72 [5.06, 8.93]	1.5e-39	972
15 years	0.02	3.20 [2.55, 4.00]	3.7e-24	387
5 years	0.01	6.04 [5.06, 7.22]	4.6e-87	287
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CARDMYO – Cardiomyopathy
GWS hits: 7

Survival analyses between endpoints

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Plot

before Cardiomyopathy
after Cardiomyopathy

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Cardiomyopathy

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