Restrictive cardiomyopathy

I9_CARDMYORESTR

restrictive cardiomyopathy: A type of heart disorder referring to the inability of the ventricles to fill with blood because the myocardium (heart muscle) stiffens and looses its flexibility. Causes include replacement of the myocardium with scar tissue, abnormal cellular infiltration of the myocardium, or deposition of a substance (e.g., amyloid) in the myocardium.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I42.5

Hospital discharge: ICD-9 4250A

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 I42.5

Cause of death: ICD-9 4250A

Cause of death: ICD-8 $!$

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

I9_CARDMYORESTR

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Parent code in ICD-10 I42

Name in latin Cardiomyopathia restrictiva

Similar endpoints

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List of similar endpoints to Restrictive cardiomyopathy based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	72	30	42
Unadjusted prevalence (%)	0.02	0.02	0.03
Mean age at first event (years)	59.01	59.70	58.52

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CARDMYORESTR – Restrictive cardiomyopathy
GWS hits:

Survival analyses between endpoints

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Plot

before Restrictive cardiomyopathy
after Restrictive cardiomyopathy

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Restrictive cardiomyopathy

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