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Cardiomyopathies, Primary/intrinsic

DOIDEFOMESHSNOMED PheWeb

I9_CARDMPRI

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

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FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 I42.0, I42.1, I42.3, I42.4, I42.5
Hospital discharge: ICD-9 4250A|4254A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 I42.0, I42.1, I42.3, I42.4, I42.5
Cause of death: ICD-9 4250A|4254A
Cause of death: ICD-8 $!$

3316

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

3316

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Check minimum number of events None

3316

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Include endpoints None

3316

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I9_CARDMPRI

Extra metadata

Level in the ICD hierarchy 4
First used in FinnGen datafreeze DF2

Summary Statistics

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Key figures

All Female Male
Number of individuals 3238 891 2347
Unadjusted prevalence (%) 1.05 0.51 1.74
Mean age at first event (years) 59.79 57.54 60.64

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.47 [3.17, 6.30] 1.3e-17 703
15 years 0.01 2.45 [1.76, 3.39] 8.4e-8 308
5 years 0.01 4.98 [3.89, 6.36] 2.0e-37 219
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CARDMPRI – Cardiomyopathies, Primary/intrinsic
GWS hits: 5

Survival analyses between endpoints

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Plot

before Cardiomyopathies, Primary/intrinsic
after Cardiomyopathies, Primary/intrinsic

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Cardiomyopathies, Primary/intrinsic

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