Cardiomyopathy (excluding other)

FG_CARDMYO

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries None

0

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Check pre-conditions, main-only, mode, ICD version None

0

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Check minimum number of events None

0

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Include endpoints

3424

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FG_CARDMYO

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Similar endpoints

List of similar endpoints to Cardiomyopathy (excluding other) based on the number of shared cases.

Venn diagram with an highlighted set fully inside another set Broader endpoints:

Venn diagram with a set fully inside an highlighted set Narrower endpoints:

Show all endpoint correlations

Summary Statistics

Key figures

All Female Male
Number of individuals 3341 920 2421
Unadjusted prevalence (%) 1.08 0.53 1.79
Mean age at first event (years) 59.46 57.20 60.32

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 6.42 [5.10, 8.09] 3.3e-56 753
15 years 0.02 3.03 [2.40, 3.82] 5.5e-21 314
5 years 0.01 4.99 [3.98, 6.26] 7.4e-44 222
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: FG_CARDMYO – Cardiomyopathy (excluding other)
GWS hits: 5

Survival analyses between endpoints

Plot

before Cardiomyopathy (excluding other)
after Cardiomyopathy (excluding other)

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Drugs most likely to be purchased after Cardiomyopathy (excluding other)