Cardiomyopathies, Secondary/extrinsic

I9_CARDMSEC

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I42.6, I42.7#

Hospital discharge: ICD-9 4258A

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 I42.6, I42.7#

Cause of death: ICD-9 4258A

Cause of death: ICD-8 $!$

125

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

125

Check minimum number of events None

125

Include endpoints None

125

I9_CARDMSEC

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Cardiomyopathies, Secondary/extrinsic based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Cardiomyopathy due to drugs and other external agents

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	123	38	85
Unadjusted prevalence (%)	0.04	0.02	0.06
Mean age at first event (years)	57.61	54.84	58.85

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CARDMSEC – Cardiomyopathies, Secondary/extrinsic
GWS hits: 0

Survival analyses between endpoints

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Plot

before Cardiomyopathies, Secondary/extrinsic
after Cardiomyopathies, Secondary/extrinsic

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Table

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Drugs most likely to be purchased after Cardiomyopathies, Secondary/extrinsic

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