Cardiomyopathies, Secondary/extrinsic

I9_CARDMSEC

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I42.6, I42.7#

Hospital discharge: ICD-9 4258A

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 I42.6, I42.7#

Cause of death: ICD-9 4258A

Cause of death: ICD-8 $!$

125

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

125

Check minimum number of events None

125

Include endpoints None

125

I9_CARDMSEC

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Cardiomyopathies, Secondary/extrinsic based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Cardiomyopathy due to drugs and other external agents

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

123

Unadjusted prevalence (%)

0.04

0.02

0.06

Mean age at first event (years)

57.61

54.84

58.85

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CARDMSEC – Cardiomyopathies, Secondary/extrinsic
GWS hits: 0

Survival analyses between endpoints

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Plot

before Cardiomyopathies, Secondary/extrinsic
after Cardiomyopathies, Secondary/extrinsic

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Cardiomyopathies, Secondary/extrinsic

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