Cardiovascular diseases (excluding rheumatic etc)

DOID EFO MESH SNOMED PheWeb

FG_CVD

cardiovascular disease: A disease involving the cardiovascular system.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

FG_HYPERTENSION

I9_ISCHHEART

I9_PULMEMB

FG_OTHHEART

FG_CEREBVASC

FG_DOAAC

FG_DISVEINLYMPH

FG_OTH

157546

FG_CVD

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Cardiovascular diseases (excluding rheumatic etc) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	152697	76397	76300
Unadjusted prevalence (%)	49.49	44.03	56.51
Mean age at first event (years)	52.62	50.34	54.89

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	4.52 [4.22, 4.83]	<1e-100	23042
15 years	0.01	2.65 [2.44, 2.87]	<1e-100	10146
5 years	0.00	3.81 [3.47, 4.18]	<1e-100	4271
1 year	0.00	19.05 [16.11, 22.53]	<1e-100	3451

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FG_CVD – Cardiovascular diseases (excluding rheumatic etc)
GWS hits: 24

Survival analyses between endpoints

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Plot

before Cardiovascular diseases (excluding rheumatic etc)
after Cardiovascular diseases (excluding rheumatic etc)

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Cardiovascular diseases (excluding rheumatic etc)

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