Pulmonary embolism

I9_PULMEMB

pulmonary embolism: The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I26

Hospital discharge: ICD-9 415

Hospital discharge: ICD-8 450

Cause of death: ICD-10 I26

Cause of death: ICD-9 415

Cause of death: ICD-8 450

6973

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

6962

Check minimum number of events None

6962

Include endpoints None

6962

I9_PULMEMB

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 I26-I28

Name in latin Embolia pulmonalis

Similar endpoints

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List of similar endpoints to Pulmonary embolism based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Pulmonary heart disease

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	6753	3440	3313
Unadjusted prevalence (%)	2.19	1.98	2.45
Mean age at first event (years)	62.62	61.03	64.27

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.08	6.06 [4.80, 7.64]	2.8e-52	1687
15 years	0.01	1.49 [1.18, 1.89]	1.0e-3	336
5 years	0.01	4.93 [4.15, 5.86]	4.4e-73	427
1 year	0.01	40.10 [34.23, 46.99]	<1e-100	857

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_PULMEMB – Pulmonary embolism
GWS hits: 7

Survival analyses between endpoints

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Plot

before Pulmonary embolism
after Pulmonary embolism

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Table

Loading survival analyses table

Drugs most likely to be purchased after Pulmonary embolism

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