Pulmonary embolism

I9_PULMEMB

pulmonary embolism: The obstruction of the pulmonary artery or one of its branches by an embolus, sometimes associated with infarction of the lung.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 I26
Hospital discharge: ICD-9 415
Hospital discharge: ICD-8 450
Cause of death: ICD-10 I26
Cause of death: ICD-9 415
Cause of death: ICD-8 450

6973

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

6962

diagram downward connector

Check minimum number of events None

6962

diagram downward connector

Include endpoints None

6962

diagram downward connector
I9_PULMEMB

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I26-I28
Name in latin Embolia pulmonalis

Summary Statistics

Key figures

All Female Male
Number of individuals 6753 3440 3313
Unadjusted prevalence (%) 2.19 1.98 2.45
Mean age at first event (years) 62.62 61.03 64.27

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.08 6.06 [4.80, 7.64] 2.8e-52 1687
15 years 0.01 1.49 [1.18, 1.89] 1.0e-3 336
5 years 0.01 4.93 [4.15, 5.86] 4.4e-73 427
1 year 0.01 40.10 [34.23, 46.99] <1e-100 857

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_PULMEMB – Pulmonary embolism
GWS hits: 7

Survival analyses between endpoints

Plot

before Pulmonary embolism
after Pulmonary embolism

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Pulmonary embolism