Venous thromboembolism

DOID EFO MESH SNOMED PheWeb

I9_VTE

Phlebitis: Inflammation of a vein.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I26, I80, O87.1, O88.2

Hospital discharge: ICD-9 415|451|6713|6714|6732

Hospital discharge: ICD-8 450|451|671|6739

Hospital discharge: excluded ICD-10 I80.0#

Hospital discharge: excluded ICD-9 4510

Cause of death: ICD-10 I26, I80, O87.1, O88.2

Cause of death: ICD-9 415|451|6713|6714|6732

Cause of death: ICD-8 450|451|671|6739

Cause of death: excluded ICD-10 I80.0#

Cause of death: excluded ICD-9 4510

14998

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

14895

Check minimum number of events None

14895

Include endpoints None

14895

I9_VTE

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Venous thromboembolism based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	14454	7768	6686
Unadjusted prevalence (%)	4.68	4.48	4.95
Mean age at first event (years)	58.01	55.87	60.50

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.16 [2.66, 3.76]	2.4e-38	2936
15 years	0.01	1.25 [1.06, 1.46]	6.2e-3	827
5 years	0.00	3.50 [3.06, 3.99]	1.6e-77	761
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_VTE – Venous thromboembolism
GWS hits: 18

Survival analyses between endpoints

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Plot

before Venous thromboembolism
after Venous thromboembolism

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Venous thromboembolism

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