Pulmonary heart disease, diseases of pulmonary circulation

DOID MESH PheWeb

I9_PULMHEART

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

I9_PULMEMB

I9_PULMOTHHD

7678

I9_PULMHEART

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Pulmonary heart disease, diseases of pulmonary circulation based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

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Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7450	3759	3691
Unadjusted prevalence (%)	2.41	2.17	2.73
Mean age at first event (years)	62.75	61.08	64.45

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.48 [3.25, 6.17]	3.9e-20	1929
15 years	0.01	1.23 [0.90, 1.67]	1.9e-1	384
5 years	0.00	4.67 [3.82, 5.70]	6.3e-52	499
1 year	0.01	37.65 [31.63, 44.81]	<1e-100	967

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_PULMHEART – Pulmonary heart disease, diseases of pulmonary circulation
GWS hits: 6

Survival analyses between endpoints

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Plot

before Pulmonary heart disease, diseases of pulmonary circulation
after Pulmonary heart disease, diseases of pulmonary circulation

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Table

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Drugs most likely to be purchased after Pulmonary heart disease, diseases of pulmonary circulation

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