Cardiovascular diseases

PheWeb

I9_CVD

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I00-I99

Cause of death: ICD-10 I00-I99

150809

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

150809

Check minimum number of events None

150809

Include endpoints

I9_RHEUFEV

I9_HYPERTENSION

I9_ISCHHEART

I9_PULMHEART

I9_OTHHEART

I9_CEREBVASC

I9_DOAAC

I9_DISVEINLYMPH

I9_OTH

171478

I9_CVD

Extra metadata

Level in the ICD hierarchy 1

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Cardiovascular diseases based on the number of shared cases.

Broader endpoints:

Co-morbidities of interest (NEURO)

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	166137	85179	80958
Unadjusted prevalence (%)	53.84	49.09	59.96
Mean age at first event (years)	51.68	49.46	54.02

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	4.79 [4.47, 5.13]	<1e-100	23424
15 years	0.01	2.76 [2.54, 3.00]	<1e-100	10367
5 years	0.00	4.13 [3.75, 4.54]	<1e-100	4281
1 year	0.00	21.02 [17.62, 25.08]	<1e-100	3431

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CVD – Cardiovascular diseases
GWS hits: 22

Survival analyses between endpoints

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Plot

before Cardiovascular diseases
after Cardiovascular diseases

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Cardiovascular diseases

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