Hypertensive diseases (excluding secondary)

FG_HYPERTENSION

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector

Filter registries None

0

diagram downward connector

Check pre-conditions, main-only, mode, ICD version None

0

diagram downward connector

Check minimum number of events None

0

diagram downward connector
FG_HYPERTENSION

Extra metadata

Level in the ICD hierarchy C
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
?
Number of individuals
85491 41601 43890
?
Unadjusted prevalence (%)
27.71 23.97 32.51
?
Mean age at first event (years)
56.97 56.82 57.11

?
Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.02 1.77 [1.64, 1.91] 4.5e-48 12851
15 years 0.01 1.05 [0.97, 1.13] 2.2e-1 5419
5 years 0.00 1.72 [1.60, 1.85] 9.8e-48 2649
1 year 0.00 6.77 [6.08, 7.55] <1e-100 1871

Age distribution of first events

01020304050607080900k2k4k6k8k10k12k14k16k18k20k22kageindividuals

Year distribution of first events

197019751980198519901995200020052010201520210k2k4k6k8k10k12k14k16kyearindividuals

Cumulative Incidence

Correlations

Index endpoint: FG_HYPERTENSION – Hypertensive diseases (excluding secondary)
GWS hits: 84

Survival analyses between endpoints

Plot

before Hypertensive diseases (excluding secondary)
after Hypertensive diseases (excluding secondary)

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Hypertensive diseases (excluding secondary)