Hypertension, Pulmonary Arterial

I9_HYPTENSPUL

hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I27.0

Hospital discharge: ICD-9 4160A

Hospital discharge: ICD-8 42600

Cause of death: ICD-10 I27.0

Cause of death: ICD-9 4160A

Cause of death: ICD-8 42600

184

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

184

Check minimum number of events None

184

Include endpoints None

184

I9_HYPTENSPUL

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 I27

Name in latin Hypertensio pulmonalis primaria

Similar endpoints

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List of similar endpoints to Hypertension, Pulmonary Arterial based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	179	123	56
Unadjusted prevalence (%)	0.06	0.07	0.04
Mean age at first event (years)	55.35	54.84	56.47

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_HYPTENSPUL – Hypertension, Pulmonary Arterial
GWS hits: 1

Survival analyses between endpoints

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Plot

before Hypertension, Pulmonary Arterial
after Hypertension, Pulmonary Arterial

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Table

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Drugs most likely to be purchased after Hypertension, Pulmonary Arterial

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