Hypertension, Pulmonary Arterial


hypertension: Persistently high systemic arterial blood pressure. Based on multiple readings (blood pressure determination), hypertension is currently defined as when systolic pressure is consistently greater than 140 mm Hg or when diastolic pressure is consistently 90 mm Hg or more.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 I27.0
Hospital discharge: ICD-9 4160A
Hospital discharge: ICD-8 42600
Cause of death: ICD-10 I27.0
Cause of death: ICD-9 4160A
Cause of death: ICD-8 42600


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 I27
Name in latin Hypertensio pulmonalis primaria

Summary Statistics

Key figures

All Female Male
Number of individuals 179 123 56
Unadjusted prevalence (%) 0.06 0.07 0.04
Mean age at first event (years) 55.35 54.84 56.47


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_HYPTENSPUL – Hypertension, Pulmonary Arterial
GWS hits: 1

Survival analyses between endpoints


before Hypertension, Pulmonary Arterial
after Hypertension, Pulmonary Arterial

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Drugs most likely to be purchased after Hypertension, Pulmonary Arterial