Diseases of arteries, arterioles and capillaries

I9_DOAAC

vascular disease: A non-neoplastic or neoplastic disorder affecting the arteries, veins, or lymphatic vessels. Examples include vasculitis, thrombophlebitis, arteriosclerosis, lymphedema, hemangioma, and angiosarcoma.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 I70-I79
Cause of death: ICD-10 I70-I79

18233

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

18233

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Check minimum number of events None

18233

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I9_DOAAC

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 20516 7020 13496
Unadjusted prevalence (%) 6.65 4.05 10.00
Mean age at first event (years) 63.89 60.96 65.41

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.06 4.98 [4.44, 5.59] <1e-100 5913
15 years 0.01 2.46 [2.18, 2.77] 1.4e-50 2317
5 years 0.00 4.51 [4.11, 4.96] <1e-100 1787
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: I9_DOAAC – Diseases of arteries, arterioles and capillaries
GWS hits: 4

Survival analyses between endpoints

Plot

before Diseases of arteries, arterioles and capillaries
after Diseases of arteries, arterioles and capillaries

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diseases of arteries, arterioles and capillaries