Aortic aneurysm

I9_AORTANEUR

aortic aneurysm: A ruptured aneurysm located in the wall of the proximal portion of the descending aorta proceeding from the arch of the aorta.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I71.1, I71.2, I71.3, I71.4, I71.5, I71.6, I71.8, I71.9

Hospital discharge: ICD-9 441[1-9]|0930A

Hospital discharge: ICD-8 0930|441

Cause of death: ICD-10 I71.1, I71.2, I71.3, I71.4, I71.5, I71.6, I71.8, I71.9

Cause of death: ICD-9 441[1-9]|0930A

Cause of death: ICD-8 0930|441

5268

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

5257

Check minimum number of events None

5257

Include endpoints

I9_ABAORTANEUR

I9_THAORTANEUR

6255

I9_AORTANEUR

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Aortic aneurysm based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	6092	1159	4933
Unadjusted prevalence (%)	1.97	0.67	3.65
Mean age at first event (years)	67.16	65.24	67.61

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.29 [3.18, 5.78]	1.5e-21	1638
15 years	0.01	1.82 [1.42, 2.33]	2.0e-6	587
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_AORTANEUR – Aortic aneurysm
GWS hits: 3

Survival analyses between endpoints

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Plot

before Aortic aneurysm
after Aortic aneurysm

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Aortic aneurysm

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