Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

FG_DISVEINLYMPH

vascular disease: A non-neoplastic or neoplastic disorder affecting the arteries, veins, or lymphatic vessels. Examples include vasculitis, thrombophlebitis, arteriosclerosis, lymphedema, hemangioma, and angiosarcoma.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

I9_PHLETHROM

I9_PHLETHROMBDVTLOW

I9_PVT

I9_THROMBOTH

I9_VARICVE

I9_VARICVEOES

I9_LYMPHADE

37232

FG_DISVEINLYMPH

Extra metadata

Level in the ICD hierarchy C

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN) based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

All

Female

Male

Number of individuals

36246

24497

11749

Unadjusted prevalence (%)

11.75

14.12

8.70

Mean age at first event (years)

47.38

44.76

52.83

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	1.34 [1.19, 1.50]	8.0e-7	4668
15 years	0.00	0.86 [0.78, 0.96]	6.3e-3	1879
5 years	0.00	1.68 [1.51, 1.86]	2.4e-23	915
1 year	0.00	6.39 [5.61, 7.28]	<1e-100	661

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: FG_DISVEINLYMPH – Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)
GWS hits: 29

Survival analyses between endpoints

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Plot

before Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)
after Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

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Table

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Drugs most likely to be purchased after Diseases of veins, lymphatic vessels and lymph nodes, not elsewhere classified (FINNGEN)

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