Oesophageal varices

DOID EFO MESH SNOMED PheWeb

I9_VARICVEOES

esophageal varices: Abnormally dilated veins of the esophagus.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I85

Hospital discharge: ICD-9 456[0-1]

Hospital discharge: ICD-8 4560

Cause of death: ICD-10 I85

Cause of death: ICD-9 456[0-1]

Cause of death: ICD-8 4560

1004

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

791

Check minimum number of events None

791

Include endpoints None

791

I9_VARICVEOES

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 I80-I89

Name in latin Varices oesophagi

Similar endpoints

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List of similar endpoints to Oesophageal varices based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	769	266	503
Unadjusted prevalence (%)	0.25	0.15	0.37
Mean age at first event (years)	58.96	57.61	59.68

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	5.94 [1.97, 17.89]	1.6e-3	221
15 years	0.01	1.89 [0.76, 4.71]	1.7e-1	47
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_VARICVEOES – Oesophageal varices
GWS hits: 1

Survival analyses between endpoints

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Plot

before Oesophageal varices
after Oesophageal varices

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Table

Loading survival analyses table

Drugs most likely to be purchased after Oesophageal varices

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