Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

PheWeb

CIRRHOSIS_BROAD

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

K11_ALCOLIV

FIBROLIV

SCLEROLIV

FIBROSCLEROLIV

CHIRHEP_NAS

I9_HYPTENSPOR

I9_VARICVEOES

3090

CIRRHOSIS_BROAD

Extra metadata

First used in FinnGen datafreeze DF3

Similar endpoints

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List of similar endpoints to Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523 based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	3009	946	2063
Unadjusted prevalence (%)	0.98	0.55	1.53
Mean age at first event (years)	57.76	56.26	58.44

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: CIRRHOSIS_BROAD – Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523
GWS hits: 4

Survival analyses between endpoints

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Plot

before Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523
after Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

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