Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

PheWeb

CIRRHOSIS_BROAD

No definition available.

Endpoint definition

↥

FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries None

Check pre-conditions, main-only, mode, ICD version None

Check minimum number of events None

Include endpoints

K11_ALCOLIV

FIBROLIV

SCLEROLIV

FIBROSCLEROLIV

CHIRHEP_NAS

I9_HYPTENSPOR

I9_VARICVEOES

3090

CIRRHOSIS_BROAD

Extra metadata

First used in FinnGen datafreeze DF3

Similar endpoints

↥

List of similar endpoints to Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523 based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

↥

Key figures

All

Female

Male

Number of individuals

3009

946

2063

Unadjusted prevalence (%)

0.98

0.55

1.53

Mean age at first event (years)

57.76

56.26

58.44

?

Follow-up

Amount of time to look for the endpoint since entering the study. This is either either 1, 5, 15 years or the full study time from 1998 to 2019.

Absolute risk

Estimates the probability of dying from the current endpoint. Check the Documentation page for Mortality: absolute risk to get more details.

Hazard Ratio (HR) and 95% Confidence Interval (CI)

Measures how much the risk of dying increases (HR > 1) or decreases (HR < 1).

Number of individuals (N)

Number of individuals having the current endpoint and died during the follow-up time.
Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: CIRRHOSIS_BROAD – Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523
GWS hits: 4

Survival analyses between endpoints

↥

Plot

before Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523
after Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Cirrhosis, broad definition used in the article https://doi.org/10.1101/594523

↥