Hypertension, portal


portal hypertension: Increased blood pressure in the portal venous system. It is most commonly caused by cirrhosis. Other causes include portal vein thrombosis, Budd-Chiari syndrome, and right heart failure. Complications include ascites, esophageal varices, encephalopathy, and splenomegaly.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None


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Check conditions None


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Filter registries

Hospital Discharge: ICD-10 K76.6
Hospital discharge: ICD-9 5723A
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 K76.6
Cause of death: ICD-9 5723A


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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 9


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Check minimum number of events None


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Include endpoints None


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Extra metadata

First used in FinnGen datafreeze DF2
Parent code in ICD-10 K76
Name in latin Hypertensio venae portae

Summary Statistics

Key figures

All Female Male
Number of individuals 56 21 35
Unadjusted prevalence (%) 0.02 0.01 0.03
Mean age at first event (years) 55.19 55.54 54.99


Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence


Index endpoint: I9_HYPTENSPOR – Hypertension, portal
GWS hits:

Survival analyses between endpoints


before Hypertension, portal
after Hypertension, portal

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Drugs most likely to be purchased after Hypertension, portal