Hypertension, portal

I9_HYPTENSPOR

portal hypertension: Increased blood pressure in the portal venous system. It is most commonly caused by cirrhosis. Other causes include portal vein thrombosis, Budd-Chiari syndrome, and right heart failure. Complications include ascites, esophageal varices, encephalopathy, and splenomegaly.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K76.6

Hospital discharge: ICD-9 5723A

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 K76.6

Cause of death: ICD-9 5723A

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 9

Check minimum number of events None

Include endpoints None

I9_HYPTENSPOR

Extra metadata

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K76

Name in latin Hypertensio venae portae

Similar endpoints

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List of similar endpoints to Hypertension, portal based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	56	21	35
Unadjusted prevalence (%)	0.02	0.01	0.03
Mean age at first event (years)	55.19	55.54	54.99

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_HYPTENSPOR – Hypertension, portal
GWS hits:

Survival analyses between endpoints

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Plot

before Hypertension, portal
after Hypertension, portal

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Table

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Drugs most likely to be purchased after Hypertension, portal

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