Diseases of the digestive system

PheWeb

XI_DIGESTIVE

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K00-K93, K77.0*B96.8

Hospital discharge: ICD-9 5[2-7]

Hospital discharge: ICD-8 5[2-7]

Cause of death: ICD-10 K00-K93, K77.0*B96.8

Cause of death: ICD-9 5[2-7]

Cause of death: ICD-8 5[2-7]

165128

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

165128

Check minimum number of events None

165128

Include endpoints None

165128

XI_DIGESTIVE

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diseases of the digestive system based on the number of shared cases.

Broader endpoints:

Any ICDMAIN event in hilmo or causes of death

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	159587	84779	74808
Unadjusted prevalence (%)	51.72	48.86	55.40
Mean age at first event (years)	45.75	44.09	47.63

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.02	2.01 [1.88, 2.15]	5.7e-89	17104
15 years	0.01	1.29 [1.20, 1.38]	7.8e-12	7546
5 years	0.00	2.19 [2.04, 2.36]	9.1e-96	3675
1 year	0.00	6.88 [6.09, 7.77]	<1e-100	2178

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: XI_DIGESTIVE – Diseases of the digestive system
GWS hits:

Survival analyses between endpoints

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Plot

before Diseases of the digestive system
after Diseases of the digestive system

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Table

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Drugs most likely to be purchased after Diseases of the digestive system

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