≡ Risteys
R7

Documentation Changelog GitHub Contact & Feedback

Diseases of oesophagus, stomach and duodenum

DOIDEFOMESHSNOMED PheWeb

K11_OESSTODUO

gastric mucosal hypertrophy: MC)nC)trier disease (MD) is a rare premalignant hyperproliferative gastropathy characterized by massive overgrowth of foveolar cells in the gastric lining, resulting in large gastric folds, and manifesting with epigastric pain, nausea, vomiting, peripheral edema and, less commonly, anorexia and weight loss.

Endpoint definition

↥
FinnGen phenotype data

321302 individuals

diagram downward connector

Apply sex-specific rule None

321302

diagram downward connector

Check conditions None

321302

diagram downward connector
diagram bullet

Filter registries

Hospital Discharge: ICD-10 K20, K20#, K20-K31
Cause of death: ICD-10 K20, K20#, K20-K31

42504

diagram downward connector
diagram bullet

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

42504

diagram downward connector

Check minimum number of events None

42504

diagram downward connector
diagram bullet diagram downward connector

Include endpoints

45374

diagram downward connector
K11_OESSTODUO

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

↥

Key figures

All Female Male
Number of individuals 43800 23885 19915
Unadjusted prevalence (%) 14.20 13.76 14.75
Mean age at first event (years) 55.01 53.51 56.80

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.06 [1.84, 2.31] 7.2e-36 5652
15 years 0.01 1.27 [1.14, 1.41] 6.6e-6 2426
5 years 0.00 2.68 [2.45, 2.94] <1e-100 1553
1 year 0.00 7.58 [6.71, 8.55] <1e-100 877

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

↥

Index endpoint: K11_OESSTODUO – Diseases of oesophagus, stomach and duodenum
GWS hits: 0

Survival analyses between endpoints

↥

Plot

before Diseases of oesophagus, stomach and duodenum
after Diseases of oesophagus, stomach and duodenum

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diseases of oesophagus, stomach and duodenum

↥