Achalasia of cardia

K11_ACHAL

No definition available.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 K22.0
Hospital discharge: ICD-9 5300
Hospital discharge: ICD-8 5300
Cause of death: ICD-10 K22.0
Cause of death: ICD-9 5300
Cause of death: ICD-8 5300

411

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

411

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Check minimum number of events None

411

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Include endpoints None

411

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K11_ACHAL

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 K22
Name in latin Achalasia cardiae

Summary Statistics

Key figures

All Female Male
Number of individuals 402 200 202
Unadjusted prevalence (%) 0.13 0.12 0.15
Mean age at first event (years) 50.21 47.22 53.17

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.46 [1.22, 4.95] 1.2e-2 46
15 years 0.01 1.12 [0.52, 2.42] 7.8e-1 18
5 years 0.00 2.11 [0.92, 4.84] 7.6e-2 13
1 year 0.00 8.84 [3.74, 20.89] 6.9e-7 10

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_ACHAL – Achalasia of cardia
GWS hits: 0

Survival analyses between endpoints

Plot

before Achalasia of cardia
after Achalasia of cardia

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Drugs most likely to be purchased after Achalasia of cardia