Other gastritis (incl. Duodenitis)

K11_OTHGASTR

gastric mucosal hypertrophy: MC)nC)trier disease (MD) is a rare premalignant hyperproliferative gastropathy characterized by massive overgrowth of foveolar cells in the gastric lining, resulting in large gastric folds, and manifesting with epigastric pain, nausea, vomiting, peripheral edema and, less commonly, anorexia and weight loss.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 K29.6, K29.7, K29.8, K29.9
Hospital discharge: ICD-9 5352|535[5-6]
Hospital discharge: ICD-8 5350[4-9]
Cause of death: ICD-10 K29.6, K29.7, K29.8, K29.9
Cause of death: ICD-9 5352|535[5-6]
Cause of death: ICD-8 5350[4-9]

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

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Check minimum number of events None

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Include endpoints None

6073

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K11_OTHGASTR

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 5860 2995 2865
Unadjusted prevalence (%) 1.90 1.73 2.12
Mean age at first event (years) 55.54 54.88 56.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.03 2.74 [2.17, 3.45] 1.6e-17 848
15 years 0.01 1.53 [1.21, 1.94] 4.5e-4 368
5 years 0.00 2.96 [2.36, 3.71] 5.8e-21 245
1 year 0.00 6.51 [4.99, 8.50] 2.5e-43 108

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_OTHGASTR – Other gastritis (incl. Duodenitis)
GWS hits: 0

Survival analyses between endpoints

Plot

before Other gastritis (incl. Duodenitis)
after Other gastritis (incl. Duodenitis)

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Drugs most likely to be purchased after Other gastritis (incl. Duodenitis)