Disorders of oesophagus in diseases classified elsewhere

K11_DISOESINOTH

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K23*

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 K23*

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

388

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

388

Check minimum number of events None

388

Include endpoints None

388

K11_DISOESINOTH

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Disorders of oesophagus in diseases classified elsewhere based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	370	191	179
Unadjusted prevalence (%)	0.12	0.11	0.13
Mean age at first event (years)	62.96	60.49	65.59

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.06	4.46 [1.89, 10.54]	6.5e-4	85
15 years	0.01	1.10 [0.43, 2.83]	8.4e-1	20
5 years	0.01	5.44 [2.62, 11.32]	5.9e-6	31
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_DISOESINOTH – Disorders of oesophagus in diseases classified elsewhere
GWS hits: 0

Survival analyses between endpoints

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Plot

before Disorders of oesophagus in diseases classified elsewhere
after Disorders of oesophagus in diseases classified elsewhere

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Table

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Drugs most likely to be purchased after Disorders of oesophagus in diseases classified elsewhere

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