Perforation of oesophagus

K11_PERFOES

esophageal disease: A non-neoplastic or neoplastic disorder that affects the esophagus. Representative examples of non-neoplastic disorders include esophagitis and esophageal ulcer. Representative examples of neoplastic disorders include carcinomas, lymphomas, and melanomas.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K22.3

Hospital discharge: ICD-9 5304

Hospital discharge: ICD-8 5304

Cause of death: ICD-10 K22.3

Cause of death: ICD-9 5304

Cause of death: ICD-8 5304

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

Check minimum number of events None

Include endpoints None

K11_PERFOES

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K22

Name in latin Perforatio oesophagi

Similar endpoints

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List of similar endpoints to Perforation of oesophagus based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	83	30	53
Unadjusted prevalence (%)	0.03	0.02	0.04
Mean age at first event (years)	57.43	55.70	58.41

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	-	-	-	-
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_PERFOES – Perforation of oesophagus
GWS hits:

Survival analyses between endpoints

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Plot

before Perforation of oesophagus
after Perforation of oesophagus

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Table

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Drugs most likely to be purchased after Perforation of oesophagus

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