Diseases of liver

K11_LIVER

liver disease: A disease involving the liver.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 K70-K77, K77.0*B96.8
Cause of death: ICD-10 K70-K77, K77.0*B96.8

7646

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

7646

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Check minimum number of events None

7646

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K11_LIVER

Extra metadata

Level in the ICD hierarchy 2
First used in FinnGen datafreeze DF2

Summary Statistics

Key figures

All Female Male
Number of individuals 8140 4003 4137
Unadjusted prevalence (%) 2.64 2.31 3.06
Mean age at first event (years) 53.18 51.93 54.39

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 0.07 5.75 [4.64, 7.11] 5.6e-58 1559
15 years 0.01 2.05 [1.68, 2.49] 8.7e-13 395
5 years 0.01 5.85 [4.94, 6.92] 5.2e-94 368
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: K11_LIVER – Diseases of liver
GWS hits: 5

Survival analyses between endpoints

Plot

before Diseases of liver
after Diseases of liver

loading spinner Loading survival analyses plot

Drugs most likely to be purchased after Diseases of liver