Toxic liver disease

DOID MESH PheWeb

K11_TOXLIV

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 K71

Hospital discharge: ICD-9 $!$

Hospital discharge: ICD-8 $!$

Cause of death: ICD-10 K71

Cause of death: ICD-9 $!$

Cause of death: ICD-8 $!$

303

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

303

Check minimum number of events None

303

Include endpoints None

303

K11_TOXLIV

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 K70-K77

Name in latin Morbus hepatis toxicus

Similar endpoints

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List of similar endpoints to Toxic liver disease based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	287	168	119
Unadjusted prevalence (%)	0.09	0.10	0.09
Mean age at first event (years)	53.09	50.86	56.24

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.41 [0.58, 10.04]	2.3e-1	43
15 years	-	-	-	-
5 years	-	-	-	-
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: K11_TOXLIV – Toxic liver disease
GWS hits: 0

Survival analyses between endpoints

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Plot

before Toxic liver disease
after Toxic liver disease

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Toxic liver disease

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