Varicose veins

DOID MESH PheWeb

I9_VARICVE

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I83

Hospital discharge: ICD-9 454

Hospital discharge: ICD-8 454

Cause of death: ICD-10 I83

Cause of death: ICD-9 454

Cause of death: ICD-8 454

24906

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

24906

Check minimum number of events None

24906

Include endpoints None

24906

I9_VARICVE

Extra metadata

Level in the ICD hierarchy 3

First used in FinnGen datafreeze DF2

Parent code in ICD-10 I80-I89

Name in latin Varices membrorum inferiorum

Similar endpoints

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List of similar endpoints to Varicose veins based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	24281	18233	6048
Unadjusted prevalence (%)	7.87	10.51	4.48
Mean age at first event (years)	45.44	43.66	50.81

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.01	0.88 [0.78, 1.00]	5.3e-2	2726
15 years	0.00	0.67 [0.60, 0.76]	2.8e-11	1225
5 years	0.00	0.98 [0.86, 1.12]	7.8e-1	403
1 year	0.00	1.76 [1.43, 2.16]	6.9e-8	130

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_VARICVE – Varicose veins
GWS hits: 68

Survival analyses between endpoints

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Plot

before Varicose veins
after Varicose veins

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Table

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Drugs most likely to be purchased after Varicose veins

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