Cardiomyopathy, other and unspecified

I9_CARDMYOOTH

cardiomyopathy: A disease of the heart muscle or myocardium proper. Cardiomyopathies may be classified as either primary or secondary, on the basis of etiology, or on the pathophysiology of the lesion: hypertrophic, dilated, or restrictive.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 I42.8, I42.9

Hospital discharge: ICD-9 4259X

Hospital discharge: ICD-8 425

Cause of death: ICD-10 I42.8, I42.9

Cause of death: ICD-9 4259X

Cause of death: ICD-8 425

2080

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

1940

Check minimum number of events None

1940

Include endpoints None

1940

I9_CARDMYOOTH

Extra metadata

Level in the ICD hierarchy 4

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Cardiomyopathy, other and unspecified based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

None

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	1901	769	1132
Unadjusted prevalence (%)	0.62	0.44	0.84
Mean age at first event (years)	57.81	57.92	57.73

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.05	3.66 [1.81, 7.42]	3.2e-4	364
15 years	0.01	2.10 [1.21, 3.65]	8.5e-3	139
5 years	0.01	5.55 [3.83, 8.04]	1.3e-19	123
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: I9_CARDMYOOTH – Cardiomyopathy, other and unspecified
GWS hits: 1

Survival analyses between endpoints

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Plot

before Cardiomyopathy, other and unspecified
after Cardiomyopathy, other and unspecified

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Table

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Drugs most likely to be purchased after Cardiomyopathy, other and unspecified

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