Neurological diseases

PheWeb

G6_NEURO

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 B02.2+, G00-G99, G71.10#, G71.11, G71.12, G71.13, G71.14, G71.15, G71.18

Cause of death: ICD-10 B02.2+, G00-G99, G71.10#, G71.11, G71.12, G71.13, G71.14, G71.15, G71.18

104282

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

104282

Check minimum number of events None

104282

Include endpoints

G6_NEUINFL

G6_NEUATR

G6_XTRAPYR

G6_NEURODEG

G6_DEMYEL

G6_EPIPAROX

G6_NERPLEX

G6_POLYNEU

G6_MYONEU

G6_CPETAL

G6_OTHNEU

110170

G6_NEURO

Extra metadata

Level in the ICD hierarchy 1

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Neurological diseases based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	106629	58631	47998
Unadjusted prevalence (%)	34.56	33.79	35.55
Mean age at first event (years)	51.98	49.65	54.82

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.03	2.63 [2.44, 2.84]	<1e-100	11967
15 years	0.01	1.61 [1.49, 1.73]	1.4e-33	5003
5 years	0.00	3.10 [2.89, 3.33]	<1e-100	3413
1 year	0.00	8.53 [7.67, 9.48]	<1e-100	2025

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_NEURO – Neurological diseases
GWS hits: 3

Survival analyses between endpoints

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Plot

before Neurological diseases
after Neurological diseases

Loading survival analyses plot

Table

Loading survival analyses table

Drugs most likely to be purchased after Neurological diseases

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