Cerebral palsy and other paralytic syndromes

G6_CPETAL

cerebral palsy: A group of disorders affecting the development of movement and posture, often accompanied by disturbances of sensation, perception, cognition, and behavior. It results from damage to the fetal or infant brain.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G80-G83

Cause of death: ICD-10 G80-G83

2421

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

2421

Check minimum number of events None

2421

Include endpoints

G6_CP

G6_HEMIPLE

G6_PARDIPLE

G6_TETRAPLE

G6_MONOPLE

G6_CAUDA

G6_LOCKEDIN

G6_PARALOTHUNS

2830

G6_CPETAL

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Cerebral palsy and other paralytic syndromes based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2722	1413	1309
Unadjusted prevalence (%)	0.88	0.81	0.97
Mean age at first event (years)	46.49	43.55	49.67

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.07	5.89 [4.67, 7.44]	1.5e-50	490
15 years	0.02	2.59 [2.04, 3.30]	8.4e-15	181
5 years	0.00	4.17 [3.12, 5.56]	4.0e-22	120
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_CPETAL – Cerebral palsy and other paralytic syndromes
GWS hits: 0

Survival analyses between endpoints

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Plot

before Cerebral palsy and other paralytic syndromes
after Cerebral palsy and other paralytic syndromes

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Table

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Drugs most likely to be purchased after Cerebral palsy and other paralytic syndromes

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