Cauda equina syndrome

G6_CAUDA

Cauda equina syndrome: Cauda equina syndrome refers to a group of symptoms that occur when some of the nerves in the cauda equina (the bundle of nerves that spread out from the bottom of the spinal cord) become compressed and/or damaged. Signs and symptoms of this condition include pain, numbness, or tingling in the lower back and/or legs; ' foot drop '; problems with bowel and/or bladder control; and sexual dysfunction. Cauda equina syndrome may be caused by a herniated disk , tumor , infection, fracture, or spinal stenosis . Treatment usually targets the underlying cause of the condition and often includes surgery to remove the material that is pressing on the nerves. Physical therapy , occupational therapy , and/or other services may be required if symptoms persist following surgery.

Endpoint definition

FinnGen phenotype data

321302 individuals

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Apply sex-specific rule None

321302

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Check conditions None

321302

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Filter registries

Hospital Discharge: ICD-10 G83.4
Hospital discharge: ICD-9 3534B
Hospital discharge: ICD-8 $!$
Cause of death: ICD-10 G83.4
Cause of death: ICD-9 3534B
Cause of death: ICD-8 $!$

238

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Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10, 8, 9 ; C.O.D: 10, 8, 9

238

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Check minimum number of events None

238

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Include endpoints None

238

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G6_CAUDA

Extra metadata

Level in the ICD hierarchy 3
First used in FinnGen datafreeze DF2
Parent code in ICD-10 G83
Name in latin Syndroma caudae equinae

Summary Statistics

Key figures

All Female Male
Number of individuals 227 149 78
Unadjusted prevalence (%) 0.07 0.09 0.06
Mean age at first event (years) 51.88 50.12 55.23

Mortality

Follow-up Absolute risk HR [95% CI] p N
1998–2019 - - - -
15 years - - - -
5 years - - - -
1 year - - - -

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

Index endpoint: G6_CAUDA – Cauda equina syndrome
GWS hits: 0

Survival analyses between endpoints

Plot

before Cauda equina syndrome
after Cauda equina syndrome

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Drugs most likely to be purchased after Cauda equina syndrome