Diseases of the myoneural junction and muscle

DOID MESH PheWeb

G6_MYONEU

No definition available.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G70-G73, G71.10#, G71.11, G71.12, G71.13, G71.14, G71.15, G71.18

Cause of death: ICD-10 G70-G73, G71.10#, G71.11, G71.12, G71.13, G71.14, G71.15, G71.18

2637

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

2637

Check minimum number of events None

2637

Include endpoints

G6_MYASTHENIA

G6_TOXMYONEU

G6_CONDEVMYA

G6_MYONEUOTHUNS

G6_MUSDYST

G6_MYOTDIS

G6_CONMYOP

G6_MITOCMY

G6_MUSCOTHUNS

G6_DRUGMYOP

G6_ALCOMYOP

G6_MYOPTOX

G6_PERIOPAR

G6_INFLAMYOP

G6_MYOPOTHUNS

G6_MYOMUSCINOTH

2699

G6_MYONEU

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Diseases of the myoneural junction and muscle based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	2611	1232	1379
Unadjusted prevalence (%)	0.85	0.71	1.02
Mean age at first event (years)	56.66	54.60	58.51

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.10	7.99 [5.70, 11.21]	2.5e-33	474
15 years	0.02	2.49 [1.75, 3.53]	3.4e-7	133
5 years	0.01	7.70 [5.87, 10.11]	5.7e-49	193
1 year	-	-	-	-

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_MYONEU – Diseases of the myoneural junction and muscle
GWS hits: 4

Survival analyses between endpoints

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Plot

before Diseases of the myoneural junction and muscle
after Diseases of the myoneural junction and muscle

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Table

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Drugs most likely to be purchased after Diseases of the myoneural junction and muscle

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