Extrapyramidal and movement disorders

DOID EFO MESH SNOMED PheWeb

G6_XTRAPYR

basal ganglia disease: A disease involving the basal ganglia.

Endpoint definition

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FinnGen phenotype data

321302 individuals

Apply sex-specific rule None

321302

Check conditions None

321302

Filter registries

Hospital Discharge: ICD-10 G20-G26

Cause of death: ICD-10 G20-G26

7093

Check pre-conditions, main-only, mode, ICD version

Look only at ICD versions H.D: 10 ; C.O.D: 10

7093

Check minimum number of events None

7093

Include endpoints

G6_PARKINSON

G6_PARKSCND

G6_BASDEGENOTH

G6_DYSTON

G6_XTRAPYROTH

7430

G6_XTRAPYR

Extra metadata

Level in the ICD hierarchy 2

First used in FinnGen datafreeze DF2

Similar endpoints

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List of similar endpoints to Extrapyramidal and movement disorders based on the number of shared cases.

Broader endpoints:

Narrower endpoints:

Show all endpoint correlations

Summary Statistics

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Key figures

	All	Female	Male
Number of individuals	7229	3704	3525
Unadjusted prevalence (%)	2.34	2.13	2.61
Mean age at first event (years)	60.68	58.46	63.01

Mortality

Follow-up	Absolute risk	HR [95% CI]	p	N
1998–2019	0.04	3.39 [2.59, 4.45]	1.2e-18	1207
15 years	0.01	2.11 [1.73, 2.58]	3.4e-13	603
5 years	0.00	3.40 [2.90, 4.00]	1.5e-50	386
1 year	0.00	5.43 [4.38, 6.75]	5.6e-53	129

Age distribution of first events

Year distribution of first events

Cumulative Incidence

Correlations

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Index endpoint: G6_XTRAPYR – Extrapyramidal and movement disorders
GWS hits: 0

Survival analyses between endpoints

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Plot

before Extrapyramidal and movement disorders
after Extrapyramidal and movement disorders

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Table

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Drugs most likely to be purchased after Extrapyramidal and movement disorders

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